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Untreated exponentially growing BY4741 and Δyca1 cells, however, were largely negative for both PI and DHR123 (Fig. 6 a).
It is noteworthy that solid tumor tissue from patient IROC013 was largely negative for expression of NY-ESO-1, despite having NY-ESO-1-specific T cells in tumor and ascites.
Triple labelling of C5b-9, P-selectin and phosphatidylserine on ADP- and A23187-induced aggregates confirmed these observations and further revealed that C5b-9-positive platelets incorporated into aggregates were largely negative for phosphatidylserine (Figure 4 C F).
We found that while few cells in control β-Gal acini (Fig 8Ac,e) displayed GADD153 staining similar to parental MCF10A cells (Fig 8Aa,b), the aberrant acini formed by MCF10A cells expressing PERKΔC were largely negative for GADD153 expression (Fig 8Ad,f and 8B).
However this matrix was largely negative for the more mature bone protein OCN, with slight staining at the periphery.
Interestingly, PDAC-associated stroma was largely negative for TIMP-1 expression, which was limited to the ducts.
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The film received largely negative reviews especially for a sequence in which a woman is killed with a power drill and De Palma shifted gears with the comic Wise Guys (1986).
The ultimate loss of phenotype appears not to be related to terminal senescence as P7 cells are still mitotic and largely negative (>85%%) for senescence-associated β-galactosidase (unpublished observations).
Regression parameter estimates were largely negative and nonsignificant for the IL-6sR.
That show opened on Feb. 13, 1983, to largely negative reviews but ran for almost six months and received five Tony nominations including one for best musical.
Its festival reviews were largely negative – in a critique for this paper, Xan Brooks described it as "a primped and simpering folly" and "extraordinarily silly, preening [and] fatally mishandled", while adding that Madonna's direction is "so all over the shop that it barely qualifies as direction at all".
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