As shown by multiple ultrathin sections of photoreceptors, RPGRIP1 localization was solely restricted to the CC, where it was largely localized throughout its ciliary submembrane region.
Although PDI-family proteins are largely localized to the endoplasmic reticulum, recent reports have described a cell surface localization and function of these enzymes [55] [57].
While the wind trio remained largely localized, the voices, building ever more sustained lines (doubtless prolonged electronically), were distributed throughout the hall.
Farther south, streams are intermittent and largely localized in the form of wadis, which are subject to seasonal flooding and terminate inland in chotts.
The film does, however, effectively summarize the evolution of environmental awareness from a largely localized phenomenon — people concerned about a city's perpetual smog or polluted river — to an international one.
Confocal microscopy revealed that LCP NPs were largely localized in hepatocytes not Kupffer cells.
Intratumoral staining was largely localized to tumor cells at the periphery of the microtumor nodules surrounded by stroma and vessels (Figure 5).
After a 4-h incubation, PNAs were largely localized in the nuclei of the cells; the mechanisms involved are still unclear.
However, in contrast to the PhCl⋯NH3 system, calculations predict that the structure of the reactive intermediate corresponds to a distonic ion-radical complex, where the radical density is largely localized on the bromine atom.
Immunocytochemical labeling of 5-HT2A receptors and confocal microscopy revealed that 5-HT2A receptors are largely localized on layer II/III pyramidal cell bodies and apical dendrites within AC.
The Sigma-1 receptor (S1R) largely localized to the endoplasmic reticulum (ER) serves as a pluripotent intracellular signaling molecule with diverse roles in the cell including ion channel modulation, stress signaling, and transcriptional regulation (reviewed in Su et al., 2016), however, the basic topology of this protein within a cell remains controversial.
