Plasma free cortisol, as the biologically active cortisol, would have been a preferable measure to serum cortisol, especially in light of the largely older, frail population studied - a population that likely has low albumin levels, significantly influencing laboratory values.
Anticoagulation for the prevention of cardio-embolism is most frequently indicated but largely underused in frail older patients with atrial fibrillation (AF).
In 1984, Ali was diagnosed with Parkinson's disease and now, aged 71, the retired boxer is frail - largely confined to a chair during the opening ceremonies of the 2012 Olympics in London, where he was a flag bearer for the sporting event.
The instrumentation is largely acoustic – it's often just that frail voice and a fingerpicked string instrument (I won't say guitar, because though it sometimes is a guitar, it often clearly isn't).
In addition, according to the large amount of published clinical trials, the risks of prescribing exercise even in this frail population are limited and the benefits largely prevail.
It's difficult not to interpret it as an affront to all those other hard-working people who directly serve the public and who, thanks largely to both the city and state's frail financial health, are working to do so much more with so much less to help those in need day in and day out.
Being worthy of touch is important when we consider that older, frailer and sicker bodies are touched largely for the purposes of care, and commonly through the protective barrier of plastic gloves.
It is important to clarify legal responsibilities for social care provision for older prisoners who are frail or unwell and whose needs are largely unmet.
Nursing home care is an inevitable care model for frail older adults in China, which is largely sponsored by the government of China with contributions from some nongovernment organizations and private investors.
Indeed, randomized trials generally have excluded older diabetic patients, in particular the frail ones, and clinical guidance has been largely based on data obtained in younger (adult) opulations, thus making the optimal therapy of T2DM in geriatric patients controversial.
