The understanding of hematopoietic cell functions has been largely established by the identification of a large number of effector genes expressed in hematopoietic cells, but has not been extensively substantiated at the AS level.
By March the composition of the top two divisions was largely established but nine vacancies remained.
Treaties with Liberia and Great Britain largely established the present boundaries by World War I.
Democracy was largely established, save that the upper houses remained elitist in franchise and membership.
Synaptic contacts are largely established during embryogenesis and are then maintained during growth.
It merely shows that legislators and interest groups operated in a framework largely established by prevailing public opinion.
Both tradition and themes were largely established by Theocritus, whose Bucolics are the first examples of pastoral poetry.
"Pirate talk" and the stereotypical image of pirates, in the end, were largely established by Treasure Island.
Largely established between 1873 and 1904, the amusement park once had more rides, hot dog stands, frozen custard stands and gin mills than Coney Island.
Then it could focus more on future technology, instead of creating competitors from scratch in industries that are already largely established, like memory chips.
The labor policies of today were largely established before most women held jobs, at a time when one middle-class income could support a household.
