Sentence examples for largely counteract from inspiring English sources

Although late INa integral per beat decreases with increasing frequencies, the high frequency (and thus an increasing late INa integral per minute) during AF might largely counteract this effect, leading to Na-dependent Ca overload Thus, it is likely that these effects of ranolazine independent of the action potential duration are important in human AF where Ca overload is also present [ 61].

In the spring of 2011, federal spending cuts forced by Republican legislators took much-needed money out of the economy: combined with the 2012 budget, it has largely counteracted the positive benefits provided by the 2009 stimulus.

Bose's insight was that acoustical problems might vary from one car model to another, but that they could be precisely known and largely counteracted for any given car.

Also, 5% [emim]OAc largely counteracted the benefit obtained by the stabilizing disulfide bridge in the temperature-dependent activity assays, but not in the stability assays.

A non-critical shear increase in the zones where the device is inserted is found, largely counteracted by the reduction in extreme values for top displacement, bending moment at the column base and amount of energy dissipated in the hysteresis of materials.

(State and local budget cuts, for instance, largely counteracted the American Recovery and Reinvestment Act).

These deleterious effects of NMDA were largely counteracted by cotreatment with rcHIP/PAP (Figs. 9 and 10).

Aging per se has an influence on skeletal muscle loss, but the metabolic impairment and functional losses can be largely counteracted by exercise training, especially by RT.

The implication is that the CIA immunisation schedule induces a decrease in Treg activity and that endogenous IFN-γ largely counteracts this decrease.

Any increase in retention afforded by the double ionization of phosphate groups is largely counteracted by the lack of retention from hydrophilic interaction.

Although the mechanical muscle stabilization by mini-agrin largely counteracts this adverse effect of Bcl2 (Fig 1A C; Fig 2A and B; Fig S2C and D of Supporting information), only a generalized inhibition of apoptosis can prevent the inflammatory response completely.