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RUK encodes an essential cell-cycle-regulated 152 kDa protein with a putative serine/threonine kinase domain and a large microtubule-binding domain, both of which are largely conserved in uncharacterized proteins from protozoa, plants, and animals.
These findings are partly in accordance with the hypothesis that salt tolerance mechanisms are largely conserved in halophytes and glycophytes, and that the large variations in their tolerance arise from subtle differences in the regulation of the same basic set of genes.
At all time intervals the loss of D atoms from M-proinsulin mirrored that from M-insulin-RR plus the C-peptide-KR, suggesting that the secondary-structure elements of M-proinsulin are largely conserved in its two component parts.
The βγ binding surface of Gs α is largely conserved in sequence and structure to that of Gi α, whereas differences in the surface formed by the carboxyl-terminal helix and the α4-β6 loop may mediate receptor specificity.
Compared to the cells transformed with the A3 clone, transcript levels for the majority of SVSP genes were largely conserved in the cell line 951T-F44.
In particular, a network comparison of the currently available interactome of P. falciparum revealed that functional modules which are largely conserved in the comparative set of other eukaryotic organisms are rudimentary present in the parasites interactome [7].
The overall complementarity of shape and chemical interactions observed between VER-150548 and Chk1 is largely conserved in Aurora A and is consistent with VER-150548 being a potent inhibitor of these two kinases.
The establishment of the self-renewing system of the intestinal epithelium is largely conserved in vertebrates.
Moreover, the domains flanking the stem-loop region are largely conserved in all the DNAs.
We suggest that the described eudicot clock is largely conserved in the monocot barley.
Arg1835 is largely conserved in mammalian BRCA1 and forms one side of the recognition pocket.
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CEO of Professional Science Editing for Scientists @ prosciediting.com