Sentence examples for largely complicates from inspiring English sources

But in this case, comparing to the tunneling regime, a new specific feature largely complicates the calculations.

Assemblers based on the de Bruijn approach may be largely complicated by sequencing errors.

This endeavour is largely complicated by the lack of a common standard.

Although most studies included a clear description of the immigrant groups, this classification varied largely, complicating the comparability of studies.

5 This was largely complicated by heterogeneity of study populations and treatment procedures as well as approaches having been used, all of which influenced the outcome.

In the last decades, the need for preventive strategies has driven multiple efforts to develop an effective vaccine, however the existence of more than 90 distinct pneumococcal serotypes has largely complicated the development and evaluation of anti-pneumococcal vaccines.

The existence of more than 90 distinct serotypes (differing in their chemical compositions, potential immunogenicity and epidemiological impact on different population groups) has largely complicated the development and evaluation of anti-pneumococcal vaccines[ 4].

The merging step may introduce errors into the middle of reads that will largely complicate the de Bruijn graph used in assembly and result in incorrect assembly results in S. parasanguinis FW213.

Detailed molecular analyses are largely complicated by the covalent linkage of C3b molecules to the target surface and the requirement of C3 convertases to generate high C3b densities [ 12].

Approximately half of all patients treated for HIV in France are affected with lipoatrophy [ 2] and choice of treatment for these individuals is largely complicated by this condition [ 3].

Disease control has been largely complicated by the emergence of multi-resistant Mycobacterium tuberculosis strains [ 4], which explains why greater attention is now being given to the diagnosis and treatment of TB in all countries, including those with very efficient health system [ 5].