Sentence examples for largely challenging from inspiring English sources

In a largely challenging review of Mr Osborne's Economic Experiment, a book by the Observer economics columnist William Keegan, Macpherson wrote in March before the campaign started: "Some of Keegan's book resonates.

Both distinct programs have been detected during in vitro hESCs/OP9 co-culturing, but it remains largely challenging to precisely define and separate these two stages [ 37].

Consecutive research largely challenged their findings—see, e.g., Burkhauser et al. (2000) and Neumark and Wascher (2000).

According to my interviews in both publishing houses, however, the non-antagonistic relations among editors have been largely challenged by the reform of the publishing industry, especially when publishing houses are changing from public institutions to companies.

Some of the women at the screening were not too pleased with the contents of said goodie bags ― especially given that "Wonder Woman" is a superhero film about female strength that largely challenges gender stereotypes.

Any progress in the genre so far has been devoted largely to challenging the heroism of the men in capes and tights.

It is a subject she said "that has largely been challenged by the overwhelming amount of documentary and architectural photography that dwells upon the ruins of the city".

Summary: Developing liquid chromatography tandem mass spectrometry (LC-MS/MS) analyses of (bio chemicals is both time consuming and challenging, largely because of the large number of LC and MS instrument parameters that need to be optimized.

Treatment of aggressive glioblastoma brain tumors is challenging, largely due to diffusion barriers preventing efficient drug dosing to tumors.

Arranging experiments to adequately test different factors is challenging, largely because of the difficulties of identifying and testing populations that differ only in the desired variables and not in others (Wiles et al. 2011).

Dengue vaccine development has proven challenging, largely because of the four different virus serotypes in circulation.