While MITA/STING plays a critical role in the cellular response to many forms of cytosolic DNA, it appears to largely augment signaling pathways involving RIG-I and MAVS [19], [21].
During early reperfusion, ROS formation from various sources, including the respiratory chain, is largely augmented.
Meanwhile, inhibiting ERK, p38 MAPK, or ROCK activation largely augmented the upregulation effect of fluvastatin (P < 0.01).
Due to the increasing demand in bone graft substitutes for the repair of bone defect and irrigularities, has largely augment in the use of biomaterial for the replacement and treatment of such defect.
The technological advancements have served largely to augment neuropsychological findings rather than to supplant them.
Digital technological development, especially in computing, communications, and data storage technologies, has augmented largely the diversity, quantity, and complexity of computational systems.
To reach the accuracy obtained by our method, the number of nodes and terms in the above two methods should be augmented largely.
As such, these de novo optical maps were largely used to augment and cross-validate optical map assemblies constructed by iterative assembly.
The remarkable thing about America is how many big companies are expanding fast largely through organic growth (augmented, admittedly, by plenty of small acquisitions).
It is suddenly possible to envisage a state of war arcing from Iraq in the east to Libya in the west, with existing – largely internal – conflicts being augmented by an old-fashioned state-to-state war between Egypt and its neighbour Libya.
