Find the chemical factors that will make a cell (a skin cell, say, or a piece of scar tissue) think it is in the womb, so it switches certain genes on and others off and becomes a new heart cell, and you can avoid the large-scale transplant altogether.
Assessment of the risk associated with specific immunosuppressive agents therefore requires the statistical power provided by large-scale transplant registries.
For example, in previous large-scale reciprocal transplantation experiments including plant origins from different climates in N and S Europe the performance of transplants decreased with distance from the home site [30].
We have designed a comprehensive genome-wide genotyping tool which enables accurate association testing and imputation of ungenotyped SNPs, facilitating powerful and cost-effective large-scale genotyping of transplant-related studies.
As with other recent custom genotyping arrays in cardiovascular diseases and metabolism as well as in autoimmune diseases, the TxArray facilitates conduct of powerful and cost-effective large-scale genotyping of transplant-related studies.
The Collaborative Transplant Study CTSS) based in Europe [ 25], the Scientific Registry of Transplant Recipients (SRTR) in USA [ 26], and the Australia and New Zealand Dialysis and Transplant (ANZDATA) registry are large-scale registries [ 27].
Few interventions have been conducted to reduce disparities in the early steps of the transplant process [ 12] and, to our knowledge, no study has described the development of a large-scale, dialysis facility-level, randomized study to improve transplant referral on a state-wide level and to reduce disparities in access to transplantation.
The major strength of our study is the large-scale population-based cohort with essentially complete ascertainment of transplants and fatal outcomes in Europe.
The trouble at NYU Langone began Monday evening as hospital officials began to detail in e-mails the spread of large-scale power failures in critical areas, including the emergency room, the transplant unit and labor and delivery.
In this regard, heterogeneous zebrafish tumors can be transplanted into multiple recipients, which allows for large-scale in vivo multi-drug screens against genotypes of interest (Chen et al., 2014).
The traditional approach to Arctic exploration had relied on large-scale forces, with a presumption that European techniques could be successfully transplanted into the hostile polar climate.
