Large-scale screens to identify protein interactions typically underperform with eukaryotic extracellular proteins.
Our results indicate that this method may be useful for large-scale screens designed to identify novel radiation susceptibility genes.
The molecular components that mediate post-transcriptional modification may, therefore, provide alternate targets for drug design and recent large-scale screens in Drosophila validate this approach.
Business people heading home at dusk may see the glowing animation on six large-scale screens at The Window Project, a storefront public art space that is part of the Digital Arts Entertainment Laboratory of Georgia State University.
RNAi may be used for large-scale screens that systematically shut down each gene in the cell, which can help to identify the components necessary for a particular cellular process or an event such as cell division.
The use of saliva also offers a cost-effective approach for large-scale screens [6].
Moreover, large-scale screens of potential inducers of the PGC specification process are difficult to implement.
These large-scale screens are generally termed high-throughput screening [33].
Large-scale screens to identify expression patterns of interest commonly use GFP or LacZ reporter genes [37].
Large-scale screens and testing in model systems have been performed in Brucella to identify virulence factors associated with the pathogenesis and virulence.
Large-scale screens of the maize genome identified 48 genes that show the putative signature of artificial selection during maize domestication or improvement.
