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Furthermore, recent advances in computational functional genomics have enabled the large-scale prediction of domain-domain interactions and have led to repositories of known and predicted domain-domain interactions such as DOMINE [ 23] and InterDom [ 24, 25].
Integration of a plethora of genomic and biochemical data enables large-scale prediction of cellular functions.
Our approach can also be used for large-scale prediction of new protein entries in the UniportKB database and of protein sequences obtained experimentally.
Large-scale prediction of promoter sequences and their contributing cis-acting elements has become routine due to recent advances in transcriptomic technologies and genome sequencing of several plants.
Daily, large-scale prediction maps provide a valuable tool to design layout and timing of seismic surveys as they allow the identification and consideration of potential spatio-temporal hotspots to minimize potential impacts of seismic surveys on Antarctic cetacean species.
A large-scale prediction for structurally characterized proteins was performed with this powerful predictor, and statistical analyses for the results indicated zinc-binding proteins have come to be significantly involved in more complicated biological processes in higher species than simpler species during the course of evolution.
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Examples of large-scale predictions of environmental concentrations of many chemicals have already been presented in [52, 53].
Therefore, large-scale predictions of soil carbon fluxes in response to fire in the boreal region must explicitly incorporate topographic features.
Not only that keeping these databases up-to-date is a difficult task, but retrosynthetic methods are also, due to their high computational demands, not suitable for large-scale predictions.
Compared with biochemical assays, the bioinformatics is more convenient and rapid for large-scale predictions of protein lncRNA associations.
While web-based predictions are easy to use on the small scale, it severely hampers large-scale predictions and makes a direct comparison of individual methods difficult.
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