Our results with unfermented beans are different from those of Cervelotti et al. in 2008 [24] who comparing the in vitro antioxidant activity and polyphenol content of finished chocolates made for standard, large scale manufactured products and for artisan manufacturing methods which used small batch roasting and stone, melangeur grinding.
The authors also present initial results from a comprehensive manufacturing and scalability trial, and demonstrate that low-cost, large-scale manufacture of hybrid joints is now feasible.
There are many hurdles before Post can scale up his process for large-scale manufacture – cell culture is not cheap – but he has high hopes.
He made machinery that allowed the large-scale manufacture of dry ice, making it possible to ship fresher food to troops overseas during World War II.
Wilkinson, in turn, used the first steam engine built by Watt and James Moulton to drive a large air pump in his large-scale manufacture of wrought iron at Broseley, Shropshire.
Spinning mule, Multiple-spindle spinning machine invented by Samuel Crompton (1779), which permitted large-scale manufacture of high-quality thread for the textile industry.
But he had not gone into large-scale manufacture by the time the Army asked for 1,000 revolvers in the Mexican War -- he had to farm out work to competitors to fill the order.
The first large-scale manufacture of guns was achieved by the North, with its industrial capacity, leaving the South as hard up for arms as earlier American armies had been.
This process was intended to produce less expensive muskets that were easier to make and repair, but worker resistance delayed large-scale manufacture of small arms using interchangeable parts until the early 1800s.
In Britain, William R. Morris (later Lord Nuffield) undertook to emulate Ford as early as 1912, but he found British engineering firms reluctant to commit themselves to the large-scale manufacture of automotive parts.
