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official, said at a House hearing in October 1999, "they are difficult to process into a lethal form and successfully deliver to achieve large-scale casualties".
The letter calls on David Cameron to look for "political solutions" and points out that wars in Afghanistan, Iraq and Libya show that "western military interventions lead to large-scale casualties, devastating destruction and huge flows of refugees".
Since early this year, the remnants of the rebel force have been cornered in a tiny enclave on the coastline, and human rights groups say both sides have fought with a disregard for large-scale casualties among civilians trapped there.
As curfew fell, the details of how the siege ended and how many people might have been injured remained unclear, though there were no reports of large-scale casualties.
During the 115-day trial, prosecutors accused the group, led by an Algerian-born Muslim cleric, Abdul Nacer Benbrika, of plotting to use weapons and explosives to attack sites including the cricket ground and railway stations with the intention of causing large-scale casualties.
In an attempt to avoid large-scale casualties during earthquakes, Dipecho – the disaster preparedness programme of the EU's humanitarian aid and civil protection operations – has devised a training programme on how to deal with disaster in primary and secondary schools in Bangladesh.
As increasing numbers of Israel's reserve soldiers are ordered out of their civilian jobs and to the front lines of combat, they are voicing growing alarm over inadequate equipment and training in the face of large-scale casualties in their ranks.
Kelen said that the new grant from DHS will support a number of critical and exciting PACER projects that hold the potential for significantly improving how the nation's hospitals and other health care resources prepare for and respond to major disasters with the potential for large-scale casualties.
The blast at the Erawan Shrine was unprecedented in the Thai capital, where smaller bombs have been employed in domestic political violence over the past decade, but not in an effort to cause large-scale casualties.
A disaster is a large scale casualty event that has been designated a disaster area by the president.
There would be fierce reprisals, say officials in Tel Aviv, if there are large scale casualties.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com