Sentence examples for large-scale assays from inspiring English sources

The liver slices and primary cell cultures are limited by supply, limited lifespan and individual variability making them poorly compatible with regulatory-accepted large-scale assays.

Finally, gene-gene interactions that suggest functional relationships between pairs of genes are being revealed by large-scale assays for genetic interactions [ 12, 13].

The 'Natural Diversity' module provides a set of templates for display of genotypic, phenotypic or other large-scale assays involving multiple features or stocks (such as germplasm).

Perhaps most importantly, SNPs can be used in parallel assays, and the cost per data point is favorable compared to other marker types (when used in large-scale assays).

Furthermore, the NS of S. meliloti interactions versus small-scale is higher than versus large-scale assays, and the overlap with the small-scale data is similar to that for the E. coli large-scale data sets.

For large-scale assays, YPD plates were inoculated with cells from each pool using a 96-pin replicator, and then incubated for 16 to 24 h at 30 °C.

But large-scale assay, large-scale investigation, is needed, definitely needed.

Effective large-scale assay harmonization efforts have already been conducted for commonly used immunological assays of peripheral blood immune cell populations [ 43, 44].

All core atg mutants, which have been previously characterized as defective in autophagy, exhibited quite low levels of ALP activity, indicating that our large-scale assay system was capable of measuring the autophagic capacity of each strain in this collection (Fig. 1A and B).

Finally, the introduction of resistance alleles from these exotic lines into an elite soybean breeding program could be facilitated by using the SNP markers associated with white mold resistance, but it would be necessary to develop a large-scale assay for rapid, reliable, and cost effective SNP genotyping.

This supports the hypothesis that combining automated large-scale assay platforms, such as ARQiv-HTS, with qHTS can add significant value to whole-organism drug discovery without increasing the time required for the primary screen (Mathias et al., 2012; Hasson and Inglese, 2013; Rennekamp and Peterson, 2013).