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In this case, machine learning and data mining techniques are applied to large toxicity data sets to identify structural alerts in an automatic and unbiased fashion.
However, high cost and sustainability issues (i.e. large toxicity) related to organic fluids call for the design of a new type of working fluids suitable for low-temperature energy recovery.
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The only report of uptake of a metal by the LC in rodents was a scanty uptake after mice were given a large toxicity-inducing dose of intraperitoneal bismuth subnitrate [ 23].
The MCR is the ratio of the total toxicity a receptor receives from its combined exposures to multiple chemicals divided by the largest toxicity it receives from any single chemical [7, 8].
The triplet cisplatin-paclitaxel-mifepristone displayed the largest toxicity, with the maximal reduction in viability, and increase in sub-diploid DNA content, while preserving the hyperploidism also observed in cells receiving cisplatin alone or cisplatin plus paclitaxel.
For example, Price & Han (2011) show how Maximum Cumulative Ratio (MCR), the ratio of the cumulative toxicity received by an individual from exposure to multiple chemicals to the largest toxicity from a single chemical, can be used as part of the WHO/IPCS Tier 1 and Tier 2 assessments.
Considering only the eight patients that actually received 90Y-OTSA101 injection, large medullary toxicity were observed.
Table 7 shows the AUC ROC results for the large Ames toxicity benchmark set.
Second, we used a large Ames toxicity classification benchmark [15] and LIBLINEAR [16] to evaluate the performance using binary hashed sparse fingerprints.
In this study, we sought to clarify the basis of differential small and large bowel toxicity following combined treatment with PDTC and 5-FU.
They assumed that susceptibility to toxic substances has an evolutionary basis and is related to phylogenetic distance and used a large aquatic toxicity database, without adjusting for allometry.
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