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No current was observed without calcium in the pipette (left), but large time dependent currents were observed (right) when calcium was added to the pipette (200 µM free calcium).
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Upon activation with 20 200 µM free intracellular calcium and symmetric NaCl solutions, the cells showed large time-dependent currents.
The multi-layer sequential mesh motion algorithm (MSM) is proposed to improve the efficiency of the volume mesh deformations, which is adequate for large-scale time dependent applications with frequent mesh updates.
In order to further reduce the computational cost for large scale and/or time dependent problems, this multi-group information undergoes additional energy group condensation into the so-called few energy group structure which may be used in a broad range of diffusion based full-core analyses.
Both are analyzed by means of a time dependent large eddy simulation in this paper.
They are many orders of magnitude heavier then any other plasma particles and they can have many orders of magnitude larger (negative or positive) time dependent charges.
Stability and bifurcation analyses were performed in this study on the turning process with a state-dependent and large time delay using the method of multiple scales (MMS).
It is established that large pressure dependent densification and little time dependent densification occur.
The stability of the ionic network under load is here investigated and it is shown that these networks show large stress relaxation at constant strain, time dependent stress-strain behaviour and rate-dependent toughness.
Large scale time-dependent particle simulations can generate massive amounts of data, making it so that storing the results is often the slowest phase and the primary time bottleneck of the simulation.
Under physiologically relevant conditions, materials derived from natural or synthetic structural proteins are characterized by nonlinear elastic responses at medium and large deformations, time-dependent or viscoelastic behavior, and display the effects of strain-induced structural changes.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com