As observed with the Otx2+/Oct4− group, further partitioning of the Otx2+/Oct4+ up) subcategory on the basis of fold changes in H3K27Ac levels, indicating that there are large subset of enhancers which show big increases in H3K27Ac, consistent with their activation and another subset that changes minimally.
The strengths of our study are the large number of patients included, both overall and in the different Bismuth classifications, when comparing plastic with metal stents, as well as the examination of bilateral stenting using both plastic and metal stents in a large subset of patients, which allowed comparisons between the outcomes.
Clinically meaningful patterns and linkages were visible; cluster I, which mostly corresponded to an ERA subset, and a large subset of cluster III, which corresponded to RF-negative polyarthritis, suggested that the clustering recapitulated expert-derived patient subtypes while stratifying patients more homogeneously.
As we stated in our original article [ 4], the replication groups strategy is used to select a large subset of preliminary results, which are then subjected to post-hoc analysis for prioritization.
Each descendant population may inherit a large subset of the ancestral haplotypes, which continue to segregate in the descendants.
We conducted this analysis on a large subset of the UK Biobank population, which included over 3000 participants from both Asian and Black ethnic groups.
Old British men formed the largest subset of acts, which Mick Jagger mentioned during the curiously short Stones set.
We study the following problem: Find a largest subset of S which can be enclosed by the union of two, not necessarily disjoint, axis-aligned rectangles R and B such that R (resp. B) contains only red (resp. blue) points.
Additionally, P300 seemed to associate with the largest subset of features, which is consistent with experimental evidence showing that P300 associates generally to enhancers [ 1, 6].
The data set contains a large subset of novel quantitative proteomic data, which have not been described previously.
