A number of large studies in various countries have examined the claim, and almost all have found it to be true, with caveats.
If these truths were so evident, there would be no need to do large studies in which people were randomly assigned to take estrogen or, for comparison, to take a dummy pill.
The only way to know if cox-2 inhibitors can prevent cancers is to test them in large studies in which some people take the drugs and others take a dummy medication for comparison.
Dr. Reiner described today's implant as a "proactive" step and "an insurance policy" that reflected what doctors have learned from large studies in recent years about the care of asymptomatic heart-disease patients like Mr. Cheney.
More broadly, when we looked at the data from all the large studies in our set, we found that, for every three hundred to eight hundred people who gained coverage, one life was ultimately saved per year.
But financing for large studies in this field is difficult to obtain, and results from long-term studies won't, of course, be available for years.
Large studies in the past have generally focused on acupuncture in adults and found similar complication rates, with serious side effects occurring in about five of every million treatment sessions.
Teva, the pill's maker, commissioned two large studies in adolescents to satisfy government concerns about selling freely to them, but in her rejection Ms. Sebelius said neither study included 11-year-olds.
Large studies in critically ill patients convincingly demonstrated the "intimate" bond between AKI and sepsis.
The three large studies in the review involved over 3,500 people.
Large studies in the screening setting showed that tomosynthesis allows the identification of more cancers than mammography and potentially reduces the number of women recalled for benign findings.
