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This is particularly important because creating a vaccine that elicits appropriate and effective antibodies against serotype 3 may be difficult because of the large size capsule this serotype exhibits.
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This characteristic limits cell loading for small capsules or, when large size capsules are produced, can negatively affect the textural and sensorial properties of food products in which they are added.
Considering the larger size capsule with sufficient temperature potential would hence be the optimal way of designing an increased energy efficient CTES (Cool thermal energy storage) system with rapid charging and discharging.
It is expected that the storage density of the EPCM would be even greater for plant size TES systems with larger size capsules, without the penalties associated with the limited scale used here.
Accordingly, the Ussing chamber technique has been refined for the study of small specimens obtained during endoscopy using capsule systems or large size biopsy forceps [ 9, 12- 16].
Administration devices such as 'pill swallowing cups' have been used to increase the suitability of tablets and capsules of relatively large size to a broader population range [27].
Owing to the large size and number of 13- cisRA capsules required to obtain the specified dose, younger children are physically unable to take the drug unless the capsules are opened and the contents mixed with food before administration.
It is impossible to visualize the entire stomach with the passive capsule currently used in practice because of the large size of the gastric cavity.
Furthermore, such capsules being foreign in nature and having considerably large size may not reflect an accurate physiology of the GI tract.
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