Sentence examples for large single dose of from inspiring English sources

The response of 14 mouse tumour sub-lines to the radiosensitizing action of a large single dose of misonidazole (MISO) has been assessed by regrowth delay.

A large single dose of nicotinamide (1000 mg kg-1) enhanced the tumour cell killing by L-PAM as measured by tumour cell survival.

Studies in experimental models also indicate that a large single dose of exposure to diesel exhaust leads to more pronounced DNA damage, compared to the effects of the same total dose administered in smaller increments over time [ 37].

The effects of one large single dose of 5-fluorouracil (FU) have been compared to the same amount given in divided doses daily over a 3- or 5-day period.

Using an in vivo/in vitro excision assay a large single dose of pyrazinamide (500 mg kg-1 i.p). was shown to enhance the tumour cell killing by cyclophosphamide.

A large single dose of MISO (0.5 mg g-1), given i.p. 30 min prior to CCNU, prolonged the t 1/2 alpha by a factor of 2.6 but had no effect on t 1/2 beta.

Large single doses of cylophosphamide are able to cause hemorrhagic cell necrosis, bringing to heart failure or even death.

Klenzner and colleagues [ 7] studied the effect of large single doses of radiation on the function of a Nucleus 24k (Cochlear Ltd., Sydney, Australia).

Such a pharmacokinetic effect could account for part of the potentiation of MEL and CY action observed in tumours with large single doses of MISO.

However, SR-2508 did enhance the response of the RIF-1 tumour to large single doses of CCNU, though not as much as MISO.

The apparent loss of flow in tumours seen after large single doses of MISO may have important implications for its use as a chemosensitizer.