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"Raising the general level of interest rates to manage a single asset price would undoubtedly have had large side effects on other assets and sectors of the economy".
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An example is the situation where a particularly effective treatment for a disease condition is associated with a large side effect profile.
For the time being, critical MDR infections often require the use of old drugs and combination therapies, which frequently induce larger side effects and morbidity.
Propantheline bromide is a non-selective muscarinic receptor antagonist with low or varying bioavailability, with less frequent dosing and a larger side-effect burden (Nabi et al 2006).
Believes HCV treatment to be non-effective (score 1) and associated with large number of side effects (score 4) § A Chi-squared and T-test was performed for qualitative and quantitative variables respectively The median [IQR] percentage of patients followed up by general practitioners was 6%[0%-35[0%-35%le the median [IQR] number of patients enrolled in each hospital center was 27[15- 60].
The tumors can become quite large, without any side effects, and are found only at autopsies conducted for other reasons of death.
"And I think it succeeded in its goals, but it also created large unintended negative side effects.
Also, once the drug is being prescribed in large numbers, new side effects not previously reported in the clinical trials become obvious.
This may be explained by the large variability of side effects between patients, which may be attributable to occurrence of symptom clusters and pharmacogenomics [ 35, 36].
One would expect that a small probability of benefit and large probabilities of side effects would call for the input of the patient in the process of decision-making.
There are large differences in side effects between various agents and there is a clear need for an international and standardized collection of post-marketing surveillance data of biologicals in the vulnerable group of JIA patients.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com