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A large search space requires more folding trajectories and therefore also more models.
Chemical product design involves a very large search space and evaluation of numerous alternatives.
Due to the large search space volume (over 27.000 Å3), 'exhaustiveness' parameter was manually set to 50.
The large search space for tuning these parameters has motivated the use of Genetic Algorithm to optimise the solution.
The stochastic techniques generate better results as compared to deterministic in large search space in low computation time.
Genetic Algorithm (GA) is a popular heuristic method for dealing complex problems with very large search space.
The large search space of potential parameter settings for leg joints means that hand tuning is not feasible in general.
To ensure sufficient coverage of the large search space between these molecules, we constructed 600,000 fibrinogen and full-length M1 protein quaternary structure models (Fig. 3a).
With the neural network model established, the mechanical parameters are recognized using a genetic algorithm over a large search space in the global range.
Similarly, the GA uses feedback from the antenna simulator to search, somewhat more effectively, the large search space of antenna configurations to find one that is acceptable.
The TNDFSP is a difficult combinatorial optimization problem, with a large search space and multiple constraints, leading to numerous infeasible solutions.
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