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This study can be regarded as the only large scale trial of anti-infective prophylaxis in vasculitis.
The CHAMP trial is the first large scale trial of cognitive behaviour therapy for health anxiety in secondary care.
The HTA CHAMP trial (07/01/26) was the first large scale trial of cognitive behaviour therapy for health anxiety in secondary care.
Within a large scale trial of a community group intervention, women were followed prospectively to document patterns of behaviour change for perinatal care.
This finding is supported by a subsequent, large scale trial of Health Dialog's care management program, which prominently featured both the use of IVR and targeting of individuals at elevated risk for preference-sensitive surgeries, found significant savings for a group in which more individual participated in health coaching and were coached more intensely compared to less health coaching [ 21].
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This trial also may provide valuable insight into the mechanisms of EPO in AKI and pave the way for further dedicated large scale trials of EPO in AKI.
Large scale trials of piperaquine for chemoprevention of falciparum and vivax malaria were conducted in several provinces.
Large scale trials of postnatal vitamin D for any disease outcome are lacking.
Historically, 28-day mortality has been used as the primary endpoint for large scale trials of critical care interventions.
The absence of any significant effects of B vitamins on major vascular events that we observed is consistent with the results of previous large scale trials of B vitamins in patients with pre-existing vascular disease, 15 16 17 18 22 23 in those at high risk of cardiovascular disease, 19 in patients with end stage renal disease, 20 or after coronary angiography.
Accumulating data from several large scale trials of patients with T2DM also point to early lipid abnormality as a major independent risk factor for the development of diabetic nephropathy [ 10], but the early effects of triglyceride and cholesterol abnormalities on renal injure in T1DM are not fully understood and the mechanisms underlying this need further exploration.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com