This is due to a significant large-scale structural alteration of the ED (Figure 3B).
Genomic instability is a frequently occurring feature of cancer that involves large-scale structural alterations.
So far, successful drug-specific predictive markers in NSCLC and in most malignancies include molecular phenotypes reflecting somatic genetic alterations; for example, small scale mutations or large scale structural gene changes.
Just the demolition costs of some of the large scale structural experiments is a significant item.
These and others are large scale structural issues that also would be well worth a serious examination.
Finally, we investigate the large scale structural properties of more than 140 reconstructed bacterial metabolic networks.
Others, however, will have to undertake the large-scale structural reforms.
Filippakopoulos, P. et al. Histone recognition and large-scale structural analysis of the human bromodomain family.
None, however, "can enable the large-scale structural morphing we've been working toward," Hall said.
The same geometry could even be applied to large-scale structural materials, they suggest.
The subject of tectonics is concerned with the Earth's large-scale structural features.
