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A digital karyotyping library of HCC was constructed and 454 Genome Sequencer FLX System (Roche) was applied in large scale sequencing of the library.
To fill this gap, we have undertaken a large scale sequencing of A. euteiches cDNAs.
In a large scale sequencing of the cDNA library, more than 5,000 clones were analyzed for coding probability with the DNATools program [39].
These data represent the first large scale sequencing of small RNAs from mature rice grain and an opportunity to assess the role of small RNAs in grain.
The large scale sequencing of thousands of genomes from disease cohorts by the next generation sequencing (NGS) techniques are expected to uncover causal gene mutations [1] [5].
We initiated an analysis of the extent of alternative mRNA editing by large scale sequencing of full-length cDNAs from the bloodstream developmental stage of T. brucei [11], [15].
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Large-scale sequencing of DNA is a new art that the consortium learned by doing it.
Large-scale sequencing of human tumours has uncovered a vast array of genomic alterations.
While the large-scale sequencing of nucleic acids is relatively robust, this information cannot be fully understood without studying the proteins – the main functional macromolecules encoded by the genome.
One of the most important challenges in contemporary microbial ecology is to assign a functional role to the large number of novel genes discovered through large-scale sequencing of natural microbial communities that lack similarity to genes of known function.
As the model cereal crop, large-scale sequencing of rice genome must play quite important roles both in theoretical research and practical application in rice breeding, which announces the opening of another new way to resolve the world food crisis.
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