This result is in accordance with the result of large-scale scanning on positively selected genes between human and chimpanzee genomes [ 44, 45].
Proteomics technologies allow for the large-scale scanning of proteins.
However, TEM is a subjective procedure and does not allow large-scale scanning of fields.
In that respect, large-scale scanning of EST databases have previously been used for identification of SNPs in genes involved in a various number of disorders [ 49- 51].
The scan took about one day to complete on 13 parallel processors, suggesting that a large-scale scan of many structures with many functional site models is actually quite efficient.
Large-scale scans of positive selection have reported on various functional groups of genes enriched in positive selection signatures, including those involved in sensory perception [ 23], olfactory receptors [ 23, 28] and spermatogenesis [ 35].
We demonstrate the usefulness of this method with large-scale scanning transmission electron microscopy image simulations of a crystalline nanoparticle on an amorphous carbon substrate.
A vast array of digitized historical documents, as old as the printed word, have become available through large-scale scanning projects, allowing new types of historical datasets to be assembled at low cost.
Since much of the world's information is in books, this means large-scale scanning.
However, the LRT is rather computationally intensive when large numbers of markers are involved, making it prohibitive for large-scale scans.
Mutation-containing Mendelian genes that cause monogenic epilepsies can be found by the power of large scale genome scans and linkage analyses that use large multigeneration, multiplex families, positional cloning, and high throughput sequencing.
