This raised the possibility of the chromatin structure being involved in large-scale regulation of transcription.
3: Chromosomal localization seems to be important in the large-scale regulation of mRNA transcripts in response to Aroclor 1254.
Here, we present a framework for studying a gene regulatory network and the large-scale regulation of transcription on the level of chromatin structure.
However, mapping the Aroclor 1254-induced transcriptome back onto the genome was useful to get insight into the large-scale regulation of transcription.
We recently mapped the Aroclor 1254-regulated transcriptome back onto the genome in order to get insight into the large-scale regulation of transcription [ 8].
Here, we found that genes regulated by Aroclor 1254, are much closer located to each other than genes distributed randomly all over the genome, which raises the possibility of chromatin structure being involved in the large-scale regulation of transcription.
This analysis shows that IPF cells undergo large scale translational regulation depending on matrix state, while control myofibroblasts show relative stability at this level of gene regulation.
The Home Office's 2014 report into the original 18 main allegations by BUAV contested the claims there was "appalling animal suffering on a very large scale, unlawful regulation by the Home Office, wholly inadequate care of animals and inadequate enforcement by the inspectorate".
In this study, we found that 121 host miRNAs displayed significantly different expressions during viral infection, suggesting that megalocytivirus altered, on a large scale, the regulation of miRNA expression in flounder.
He mixes energy efficiency (tightening valves, better light bulbs) -- a crucial cost-reduction strategy that can only be achieved at large scale with smarter regulations and technology deployment strategies that McCain does not support -- with classic offsets (no till farming), a non-strategy.].
