The Catalogue of Somatic Mutations in Cancer (COSMIC) (32) focuses on curating information on somatic mutations in human cancer largely from Cancer Genome Project at the Sanger Institute, UK, TCGA and other large-scale published projects.
It was never our intention to make Biology Direct a large scale publishing operation, similar to, for instance, PLOS One.
While typical studies are conducted on a large scale and published in academic journals, personal science experiments involve a single patient (you) and are focused on delivering highly practical and useful pieces of information.
To date, there are few large scale studies published in the literature [ 10, 11] and none have been conducted among veterans enrolled in the Veterans Health Administration VHAA).
However, only few studies deal with the efficacy of sonographic abdominal screening (Bassères et al, 1995; Bastien et al, 1997), and there are no large scale reports published on the usefulness of ultrasonography of the peripheral lymph nodes for screening purposes.
In 1911 Grainger finally felt confident enough of his standing as a pianist to begin large-scale publishing of his compositions.
Given the times we are living through, bold large-scale publishing is more important than ever, lest The Tea Party -- who know how to work and fund the democratic technicalities of our government, gain Major Power.
A larger scale study published in 2002 in the USA reported on a national survey exploring the international student experience completed by 24 different Schools of Nursing [ 26].
A large scale phylogenetic analysis published in 2005 showed Rhodotus to be in the "core Euagarics clade", a name given to a grouping of gilled mushrooms corresponding largely to the suborder Agaricineae as defined by Singer (1986), but also including taxa that were traditionally classified in the Aphyllophorales (e.g., Clavaria, Typhula, Fistulina, Schizophyllum, etc).
However, no large scale studies are published at this time.
Internet or web-based interventions have been shown to deliver efficacious psychological intervention programs for depression on a large scale, yet no published studies have evaluated their impact among patients with co-existing physical conditions.
