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'large scale problems' is correct and usable in written English
You can use it to refer to issues that affect a large number of people or things and are difficult to address. For example: "The pandemic has raised large scale problems that governments around the world struggle to solve."
Exact(16)
This diagonalization is expensive for large scale problems.
As a result, the TALA is able to maintain computational feasibility, even for large scale problems.
We can also use the iterative method to solve large scale problems.
Thus, it is computationally extremely expensive to apply global collocation method to large scale problems.
Also, algorithms with lower complexity are easier to be extended to large scale problems.
The proposed algorithm shows much higher efficiency than the Lingo 8 software in large scale problems.
Similar(43)
"We should not forget the large-scale problems or current economic issues here".
"There will definitely be a hue and cry here, strikes and large-scale problems.
Nevertheless, large-scale problems often require parallel computation on supercomputers or clusters of small computers that share the work.
You will be solving real-world, large-scale problems.
The software is designed carefully to handle large-scale problems.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com