Sentence examples for large scale loss of from inspiring English sources

Few professions can sustain this imbalance and the large scale loss of talent.

Mr Parker said in a speech at the MI5 headquarters in London that extremists still wanted to "cause large scale loss of life" by targeting transport networks and landmarks.

He told the the Royal United Services Institute (RUSI): "We still face more complex and ambitious plots that follow the now sadly well established approach of Al Qaeda and its imitators - attempts to cause large scale loss of life, often by attacking transport systems or iconic targets.

Large scale loss of aquatic species has been witnessed due to uranium contamination.

An example of this is the Mississippi basin where there has been a large scale loss of wetlands and water quality deterioration over the past century.

It is worth remembering that military action in Libya began before a Commons vote because there was said to be an imminent threat of large scale loss of life in Benghazi.

More generally, this study also highlights the interest of large scale loss-of-function screens for characterizing the molecular mechanism of action of environmental contaminants.

In our pursuit to uncover novel synthetic lethality targets of the MYC signaling pathway, we conducted a large scale loss-of-function RNAi screen in L-MYC-overexpressing lung fibroblasts and their isogenic controls.

We have carried out a large-scale loss-of-function screen to identify genes that are required by KRAS-transformed colon cancer cells, but not by derivatives lacking this oncogene.

Genome-editing technologies have recently emerged as powerful tools for large-scale loss-of-function studies in zebrafish and will provide new ways to assess tumor suppressor function in zebrafish cancer.

Database URL: http://hts.cancerresearchuk.org/db/public RNA interference (RNAi) is a natural mechanism for gene silencing that is now widely used in large-scale loss-of-function screening campaigns in the form of small-interfering RNA (siRNA) libraries that can be used to knock down genes in a high-throughput manner.