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However, ground measurements only represent a few square metres, and its application at a large scale is difficult.
Current techniques for measuring teat morphology are subjective, not always accurate and time consuming, and gathering such information on large scale is difficult.
The moringa oil extraction in large scale is difficult and its use in industrial scale is not known, but a study using pilot plant of extraction of moringa oil with carbon dioxide as supercritical fluid is reported in literature [5] and this resource shows itself as alternative to the difficulty of obtaining moringa oil.
Studies of earliest presenting symptoms in national databases are challenging because manual free text searching on a large scale is difficult.
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Data sharing, especially on a large scale, is still difficult and time consuming.
RCTs are not usually conducted at scale because they are very expensive, prohibitively difficult, and randomisation to intervention and control groups on a large scale is practically and politically difficult.
However, restoring biodiversity in degraded landscapes on a large scale is technically demanding and usually financially difficult (Menz et al. 2013).
The death of animal populations on a large scale was also very difficult for pastoral farmers to cope with (Hall et al. 2004; Jenner 2007).
This study clearly shows that reaching prevention targets on a larger scale is very difficult to achieve.
First, global evaluation of the effects of experimental manipulations across all manual, event-based and automated endpoints in a large scale study is difficult using traditional bar or line graphs (see Fig. S1 of the Supplementary Material) and may be markedly improved by 3D swim path reconstructions proposed here (Fig. 2, 4 6).
DOI: http://dx.doi.org/10.7554/eLife.01120.012 The predicted ligands and prediction method will increase the speed of receptor odor decoding and allow for interpretation of data at a large scale that is difficult to achieve.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com