Big Science is characterized by large-scale instruments and facilities, supported by funding from government or international agencies, in which research is conducted by teams or groups of scientists and technicians.
At present, many researchers focused on the point-of-care testing (POCT), a method of disease markers detection without large-scale instruments and specialized persons.
Developing and standardizing a large-scale instrument requires a substantial amount of resources, so if these are not available the only recourse is the use of "borrowed" standardized tests.
In the enzymatic hydrolysis and C5-C6 co-fermentation sthee, the data were converted according to the results obtained from batch experiments performed in a shake flask instead of a large-scale instrument.
The resultant environments resemble large scale specialized instruments.
Due to its compatibility with even delicate surgical instruments, the process can be integrated into the large scale reprocessing of instruments in a central sterile supply department.
Genotyping with microsatellites markers on large scale using DNA sequencing instruments demonstrated very high accuracy of allele sizing and binning to avoid the scoring errors.
According to Kleiser [ 10], it is not easy to measure nutrition and physical activity in large scale studies, as the instruments used for measuring are too crude to allow the drawing of conclusions.
The large scale implementation of interRAI instruments across the continuum of care in Canada offers a new opportunity to estimate the prevalence of a broad range of neurological conditions in home care, nursing home, and hospital settings [ 16- 22].
Examples from applications of PRISMS to wall paintings at a UNESCO site in the Gobi desert are presented to demonstrate the potential of the instrument for large scale 3D spectral imaging, revealing faded writing and material identification.
Both instruments resolve the large scale features as well as the intermediate scale fluctuations inside the plasma bubbles and agree well in the absolute densities measured.
