Although large-scale industrialization began only about 1930, partly through the use of forced labour, Qaraghandy is now a major industrial centre of Kazakhstan.
The decision in 1927 to undertake rapid and large-scale industrialization required the centralizing of control, since only the government could undertake the task of marshaling the productive resources of the country to achieve its ambitious aims.
In Europe, processes related to the large-scale industrialization of agriculture threaten such bio-cultural refugia.
This so-called "game changing" technology has met, one after another, many impediments on its way to large-scale industrialization [40].
However, there are two main barriers before large-scale industrialization, i.e. low initial coulombic efficiency (ICE) and high cost caused by low carbon yield of precursors.
Importantly, AuNPs loaded in EP-FDU-12 catalyst exhibited remarkably long lifetime (>550 h) without obvious mass-specific activity decrease and poisonous coke formation, which will light the path for the large-scale industrialization of fine chemicals over noble metal catalysts.
The Fennomans in particular aimed to include the common people in a nonpolitical role in order to reduce unrest due to social problems; peasants and clergy had taken up the cause of the commoners, before the large-scale industrialization.
Until recently, the wealth of complete genomes available in public databases was decoded via the large-scale industrialization of the Sanger dideoxy chain-termination sequencing method [ 45, 46].
However, the low efficiency and high cost of existing enzymes converting lignocellulose to fermentable sugars still limit the large-scale industrialization of cellulosic ethanol at present.
For that reason, more attention is being paid to the utilization of crude glycerol from biodiesel production in order to defray the production cost of biodiesel and to promote biodiesel industrialization on a large scale.
