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"large scale impact" is a correct and usable phrase in written English.
You can use it to describe the effects or consequences of something that is big and wide-reaching. For example, "The new environmental regulations could have a large scale impact on the industry."
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The large scale impact is distributed and may spread to upstream transmission network.
This paper has discussed properties of RCA, the effects of RCA use on concrete material properties, and the large scale impact of RCA on structural members.
This paper discusses the properties of RCA, the effects of RCA use on concrete material properties, and the large scale impact of RCA on structural members.
(Sriram et al. 2006) studied the large scale impact of BGP peering session attacks that can cause cascading failures, permanent route oscillations or the gradually degrading behavior of the routers, using an Autonomous System (AS) level topology which was down-sampled from a typical AS-level topology consisting of 23,000 ASs and 96,000 BGP peering links (Zhang 2013).
Young people are growing up with the fact of their own personal capacity to turn their ideas into novel big-wide-world, large scale impact in a way many of them seem to consider not remarkable, but just business as usual.
However, with the notable exception of all-trans retinoic acid (ATRA) in a subset of AML known as acute promyelocytic leukaemia (APL [10], and imatinib mesylate (Glivec) and its derivatives in chronic myeloid leukaemia (CML [11], few of these therapies have as yet had a large scale impact.
Similar(50)
Much remains unknown about the large scale impacts of plastic debris on ecosystem functions and human health, among other information gaps.
DSB detection by γ-H2AX foci has been used in studies of the effects of personal exposure to environmental agents such as air pollution, food toxins and industrial chemicals, all of which have the potential of large scale impacts on human populations as well as populations of other organisms.
The results presented here suggest that the processes occurring in riparian peatlands in headwater catchments are less evident at larger scales which may have implications for the larger scale impact of peatland restoration projects.
At such size scales the bowl shaped crater formed in ductile materials, or in larger scale impacts, is here surrounded by a large spallation zone due to the brittle nature of the ice.
But that model may not be enough for Toms to make the large-scale impact that Mycoskie envisions.
Related(20)
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com