Sentence examples similar to large scale imbalances such from inspiring English sources

Genomic regions involved in large-scale imbalances such as trisomies or monosomies were analyzed separately by removing data from trisomic or monosomic tumors.

In order to exclude any effect of large-scale imbalances (such as trisomies or monosomies), the gene-centered CGH/expression correlations were computed in the relevant genomic regions only for tumors without the large-scale imbalances.

In addition, large scale chromosomal imbalances such as gain of chromosomes 1q and 7, and losses of 10q and 13q, reported at high frequencies in primary tumours [24], are present within these cell lines.

Clinical behaviour of these tumors, ranging from spontaneous regression to rapid progression and death due to disease, is highly correlated with a number of genomic alterations involving ploidy, MYCN amplification (MNA), and large-scale genomic imbalances such as loss of chromosome 1p, 3p, 11q and gain of 17q.

The detected large-scale imbalances were either recurrent or appeared only once in our samples.

Species with heteromorphic sex chromosomes face the challenge of large-scale imbalance in gene dose.

Such large scale conversations and such rapid mobilization of the public were not possible before the advent of social networking.

Clarke composed no large scale works such as symphonies.

He sees it as a solution for regions with large scale rehousing needs, such as Bangladesh.

A number of large scale chromosomal imbalances, including loss of either 1p or 11q or gain of 17q, are also associated with poor survival [3] [5].

These studies have revealed that large scale chromosomal imbalances result in dysregulated miRNAs which have a functional role in neuroblastoma pathogenesis and tumorigenicity.