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Avahan is a large scale HIV prevention programme in six states of India which have a population of about 300 million.
We demonstrated that nested observational studies allow for the collection of detailed behavioral data in real time with large scale HIV prevention trials.
We conducted two site preparedness studies for future large scale HIV prevention trials, and an HIV prevention phase III clinical trial of the vaginal diaphragm in cohorts of women drawn from rural, semi-rural and urban communities in KZN.
Regarding project implementation, our findings suggest that competition between NGOs may be an important determinant of technical efficiency, as having several NGOs operating in the same area can help improving the overall efficiency of large scale HIV prevention projects.
Large scale HIV testing also helps and contributes to increasing awareness of HIV prevention by promoting safe sexual behaviors including condom use, and it has shown to reduce HIV incidence rates among MSM [ 32- 34].
The M-BRiHT study demonstrates the feasibility of implementing large scale HIV screening within the Emergency Department and highlights the importance of offering choice of counselor when automated systems are employed to optimize HIV testing rates.
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Our study result further shows that Yunnan MSM students and retired MSM are particularly vulnerable population to HIV infection compared with other MSM populations, large scaled HIV screening should be prioritized for these group [ 32].
Nearly 30 large-scale HIV prevention studies have failed, making these results that much more heartening.
Many in the global community thought that large-scale HIV prevention and treatment programs couldn't be successfully implemented in the region.
Recent statistics reveal we are making real and meaningful progress in the fight against the spread of HIV/AIDS: over the past eight years, new HIV infections are down by 17percentt, in part due to large-scale HIV prevention efforts.
Now leaders face a new challenge: sustaining large-scale HIV prevention programs.
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