Without extensive control measures, large-scale emergence of vancomycin-resistant S. aureus (VRSA) may be the next stage in the global crisis of antimicrobial resistance.
Additionally, large-scale emergence and reemergence have been recently reported in many Mediterranean countries, including Morocco (1, 3 ).
That in turn could see the large-scale re-emergence of double taxation, where two countries seek to tax the same corporate income.
Large scale analysis of structure activity relationships and screening data is enabling the emergence of chemogenomics approaches to understanding the relationships between chemical space and biological target space.
However, the emergence of next generation sequencing has paved the way for large scale sequencing of several non-model plants which can be valuable in investigating the basis of medicinal properties of such plants.
The ecfA 40 kb locus could thus have contributed to the emergence of the hyper-virulent ET12 infra-specific clonal complex by driving a large scale inversion of chromosome 1.
As illustrated in Figures 2a-2b, a large scale use of treatment (combined with isolation) suppresses the spread of the sensitive infection quickly, but leads to the emergence and spread of resistance that causes the first wave of infection.
Large scale sequencing of eukaryotic genomes and the knowledge of AS being an important player in controlling gene regulation has seen the emergence of several efforts [ 3- 9] to create bioinformatics resources on alternative transcripts and protein isoforms [ 11].
In the case of the emergence of such a virulent strain, it is anticipated that antivirals would be employed on a large scale as part of an effort to contain infection spread.
This results leads us to conjecture that arch filament systems and active regions coronal loops do not result from the smooth emergence of large scale Ω-loops, but rather from the rise of flat undulatory flux tubes which get released from their photospheric anchorage by reconnection at BPs, which observational signature is Ellerman bombs.
The constantly increasing demand on quarries harms the general structure of the earth thus causing the emergence of large scale environmental problems.
