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This difference in synteny reflects the previously documented 4AL/5AL translocation [ 13, 26] and no other large scale differences in syntenic blocks were observed.
An accepted method of identifying large scale differences in gene expression is to use EST abundance as an indicator of transcript abundance.
However, there are no data to suggest large scale differences in coding or patient case mix over time or between the two groups during the study period.
Most of the differentially expressed genes on the microarray were not related to sex function, suggesting large scale differences in gene expression between the sexes are present early in development.
To examine large scale differences in gene expression between life history stages, we used the more extensive dataset from A. palmata to compare large-scale patterns of gene expression in the four major life history stages that we sampled (egg, early planula stage, late planula stage, and adult).
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There is a large scale difference in attending a concert and watching it from the comfort of your own home.
Overall, we note large-scale differences in the regulation of regulons as determined by different sets of putative transcription factors in these species.
No large-scale differences in the bacterial communities of calves that did or did not develop IBK were observed in our population.
Our findings suggest that large-scale differences in habitat preferences can occur between sympatric bat species that are virtually identical in flight morphology; hence morphological differences may be a weak indication of ecological differences between taxa.
Even if it is true that only a few genes are relevant to the differences in behavior that we find, our results indicate, under the conditions studied, that the mechanism leading to the large-scale differences in gene expression is resulting in a previously unrecognized global level of change.
This variation includes large-scale differences in gene content between ecosystems as well as within-population sequence heterogeneity.
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