Sentence examples for large scale clinical application from inspiring English sources

The RBP4 MSIA demonstrated in this study is both high throughput and automated (ideal for large scale clinical application), and since the MS analyses are performed on the intact immuno-affinity captured protein there is no need for time consuming and costly proteolytic digestion.

Here we present the first large scale clinical application of our proteomics technology to discover blood protein biomarkers in a large multi-center case-control study conducted in archived samples from 1,326 subjects from four independent studies of non-small cell lung cancer (NSCLC) in long-term tobacco-exposed populations.

Future research is needed to investigate whether an equally marked improvement can be achieved in a large scale clinical application study, ideally one comprising all the departments involved in admission and assignment planning.

Cryopreservation of tissue engineered bone (TEB), whilst maintaining its osteogenic ability, is imperative for large-scale clinical application.

It is believed that when only a new non-viral method is explored, the large-scale clinical application of gene therapy would be allowed.

Despite the tremendous improvement in efficiency and efficacy of biomaterials-assisted regenerative medicine, underlying therapeutic mechanisms have not been clearly understood, which renders safety a main concern for large-scale clinical application.

Here we present a comprehensive clinical biomarker study of lung cancer and the first large-scale clinical application of a new aptamer-based proteomic technology to discover blood protein biomarkers in disease.

Transplantation of cardiac stem/progenitor cells to improve cardiac function is theoretically plausible, but limited cell sources and possible rejection in allogeneic transplantation prevent large-scale clinical application.

Vallittu et al, 19 who previously validated the MxA-EIA for monitoring MS patients treated with IFN-β, concluded the EIA favourable for large-scale clinical application due to its high level of standardisation and reproducibility.

This was especially important to assess the HRQOL in brain tumor patients who suffered visual disorder or abnormal cognition or who were illiterate or children, thus it supported the possibility of large-scale clinical application of the questionnaire.

In general, not all TNBCs have a basal-like phenotype and not all basal-like breast cancers are TNBCs [ 2], but TNBC takes the place of the basal-like breast cancer in the application of clinical diagnosis and treatment as a result of realistic feasibility that immunohistochemical method is more feasible for large-scale clinical application or retrospective studies than gene expression signature.