Urbanisation is a dynamic complex phenomenon involving large scale changes in the land uses at local levels.
The zoning algorithm was effective at identifying large scale changes in values across 87Sr/86Sr and Sr/Ba ratio profiles.
Landscape alterations with large-scale changes at the level of infrastructures, countries or cultures, where old technologies are replaced by new systems, often along with rule changes.
"We realized that unless public opinion at some large scale changes, public transit is going to look the same or even worse 50 years from now," Logan says.
There were no large scale changes observed in the karyotype.
Hence, the Ministry of Education should look for other alternatives in making sure that the attempt to effect large-scale change at the classroom level is achieved smoothly and successfully.
These results suggest that the increase in brain metastatic ability of breast cancer cells elicited by fluoxetine treatment is not modulated via large-scale changes in ECM either at synaptic sites or in PNNs.
Identifying the genes that underlie and orchestrate this transformation, and understanding how sex-specific gene regulation is integrated into these processes will provide insight into how large-scale changes in morphology are directed at a molecular-genetic level.
Finally, these events could lead to the redistribution of chromatin regulators and consequent large-scale changes in chromatin organization, already hinted at by the loss of constitutive heterochromatin at centromeres [ 36].
Ultimately, to bring about large-scale changes in practice, information on performance at all levels will need to be made routinely available a process that will require substantial changes in health information systems, including automated entry of essential data for clinical decision-making [ 24].
Firstly, such an analysis is likely to be exploratory, in the sense that testing regions are not pre-defined, a key requirement for our method, and secondly, because BSmooth has proved adept at identifying large-scale changes in this setting and is computationally cheaper.
