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These seven unconventional disciplines are decoded from studying how people with virtually no money, or sector expertise, created large scale change and innovation to achieve global impact.
Physical preventive measures may, however, involve large-scale changes, and they can entail complex and costly investments that require a long-term perspective.
The improvement of platforms, especially the broadening application of expression microarrays and characterization of mutants with relevant phenotypes (e.g. fancl nkhg10aEt/ nkhg10aEt [ 128], nanos3 fh49/fh49 [ 129]), has allowed researchers to start looking for large-scale changes and study the involvement of major developmental pathways.
Some large scale changes like gene duplications and genomic rearrangements have, however, occurred within the galliform lineage.
Thus, following the process of SSCs dedifferentiation back to gonocytes/PGCs and transdifferentiation into oocytes, the X chromosome might be subjected to large scale changes in gene expression and epigenetic modifications.
The zoning algorithm was effective at identifying large scale changes in values across 87Sr/86Sr and Sr/Ba ratio profiles.
"Achieving sustainable and large scale changes in society can only be done through collaboration between sectors.
Several reasons related to large scale changes in exposure to risk factors and to improvements in diagnosis and treatment may explain these trends.
If temperatures go above 2C, we will risk melting of the Greenland ice sheet and other large scale changes.
The spatial organization of the genome plays an important role in the regulation of nuclear functions and undergoes large scale changes during differentiation.
The observed temporal trends give clues about large scale changes in exposure to risk factors, and to improvements in opportunistic early diagnosis.
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