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However, large scale cell culture in C. elegans has been limited to embryonically derived cells [5], [6].
Despite this prolonged and severe fragmentation of DNA however, no large scale cell death was observed in either group.
Some studies [27], [28], [29] have linked OX1R with the apoptotic pathway, where orexin stimulates OX1R to induce large scale cell death in cancer cell lines.
Large scale cell growth followed by induction at 37 °C and cell harvest two hours after induction was found to result in the highest yield of active protein.
No large scale cell death was apparent, which suggests that at this concentration, the main deleterious effect of mDUX is to interfere with cell and tissue movements, in addition to any effects it may have on myogenesis.
A fundamental element necessary to exploit the potential of ES cells in drug discovery applications and regenerative medicine is the translation of cost-effective cell culture protocols into large scale cell expansion methods.
Similar(52)
They find that repeated instances of large scale cell-death, such as might arise during therapeutic intervention or host response, strongly select for the migratory phenotype.
We find that repeated instances of large scale cell-death, such as might arise during therapeutic intervention or host response, strongly select for the migratory phenotype.
After 8 d, large-scale cell lysis occurred because Tanfloc had substantially decomposed.
In each case the need for large-scale cell culturing will be described and the experience with bioreactors reviewed.
In addition, the cell culture/CPE method requires large-scale cell culturing and a substantial amount of time.
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