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These efforts will support existing initiatives such as ELIXIR (http://www.elixir-europe.org) and BioCreaTiVe in facilitating the curation of large-scale biological databases and ontologies, together with the aggregation of workflows and services.
Many features of the InterMine system have been designed to lower the effort required for the setup and maintenance of large-scale biological databases, and these are outlined later in the text and discussed in more detail in the Supplementary Material.
Summary: Manual curation and validation of large-scale biological pathways are required to obtain high-quality pathway databases.
The iCTNet2 database collects a variety of large-scale biological datasets from public repositories to facilitate the building, visualization and analysis of heterogeneous biological networks.
Supporters of the spending increase cite studies that project apocalyptic tolls from a large-scale biological attack.
Large-scale biological engineering data increases the system control complexity.
Predicting gene functions by integrating large-scale biological data remains a challenge for systems biology.
One challenge of comparing large-scale biological datasets is the unification of gene names; otherwise, researchers spend a lot of effort in converting gene IDs when searching different databases.
However, in the data analysis of large-scale biological knowledge network, there are many problems across multiple biological domains.
They integrated data on large-scale biological network and made Petri-net model from the biological network.
Large-scale biological screens, such as the CPT Project, create huge amounts of raw data.
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