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Only in 5WexGF intestines, both SI and LI, large scale alteration of chemokine signaling was observed.
This suggests an extensive and large scale alteration of the metabolic system in the SPF small intestine.
In all 3 groups, the profiles of SI were characterized by large scale alteration of EGF, platelet-derived growth factor (PDGF) and NGF/neurotrophin signaling.
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Chromosomal abnormalities, that is to say large scale alterations to the DNA, be they deletions, duplications or translocations, can have more severe effects.
Transcriptome studies have shown that large scale alterations of transcript abundances is a common feature of Fe deficiency and thus plays a key role in the Fe deficiency response [ 15- 17].
Ten samples show large scale alterations in the CN of chromosome 6, including 6 samples with a baseline CN of 3, and one more with a baseline CN of 4. Six of the chromosomes show large regions of relative LR loss in the q-arm, with the common region spanning 159 Mbp to the q-term (170 Mbp).
We further hypothesize the presence of a larger scale alteration around this period, which is beyond all phenomena described.
In western Pacific islands, this is partly causal of the ongoing large-scale alteration of coastal zones to aquaculture.
Large-scale alteration of gene expression in psoriasis plaques is driven, in part, by differences in the composition and abundance of cell types present within lesional and non-lesional skin [ 6, 12].
Yet still, many portions of the sage-grouse's range are experiencing large-scale alterations.
We studied daily survival rate [DSR] of greater sage-grouse (Centrocercus urophasianus) from 2008 to 2010 in an area in Wyoming experiencing large-scale alterations to the landscape.
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