PDZ domains were, for instance, found to have highly diverging membrane-binding behavior despite high sequence similarity (Chen et al., 2012) and PH domains span a large range of binding affinities though being structurally very similar (Lemmon and Ferguson, 2000; Singh and Murray, 2003).
In conclusion, structurally simplified models are well suited for a large range of cardiac modeling applications.
Nano-rippled graphene, a structurally modified graphene, presents a novel material with a large range of possible applications including sensors, electrodes, coatings, optoelectronics, spintronics and straintronics.
These β,γ-CXY-dNTP analogues, each having a different leaving group mimicking PPi, can be structurally tuned by varying the X and Y substituents to exhibit a large range of the BP leaving group conjugate acid p Ka4 values.
Notable societies: Large range of sports clubs.
Reaction conditions are found general to synthesize wide range of structurally variant alkoxymethylphosphonium iodides in high yield (70 91%).
We find that all network properties offer support to the superiority of the GEO-3D network model to a large number of RIGs that correspond to a wide range of structurally diverse proteins, constructed using various contact types and a wide range of distance cut-offs.
Recently, we developed a range of structurally unique, synthetic nonsaccharide GAG mimetics (NSGMs, see Supporting Information Figures S1 and S2 for structures).
Such compounds are known to occur naturally in some plants and represent a range of structurally different chemical classes.
These compounds spanned a range of structurally different chemotypes with moderate variation in binding affinity.
