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There is some indication from climate modelling that the Mediterranean, central America and Western Australia regions may experience reduced precipitation, but there is still considerable uncertainty as climate models do not all agree, because local features such as mountains and rainforests can be important, and because of the large range of natural variability.
Torsten Mau explained to Next Wave that Boehringer Ingelheim "still take a large range of natural scientists, and a PhD is considered advantageous, but should not be mutually exclusive of communication skills".
The recently sequenced genomes of several Aspergillus species have revealed that these organisms have the potential to produce a surprisingly large range of natural products, many of which are currently unknown.
The development of the algorithm aimed at achieving high quality results for a large range of natural textures, incorporation of the original samples in the synthesis product, ease of use and good texturing speed even with input sample data two magnitudes larger than used by previous techniques.
We speculate that there is a large margin in the amount of expressed MHC class I needed to protect normal cells from being killed by NK cells, which may reflect a need to secure self tolerance over a large range of natural variations in MHC class I expression.
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With reasonable estimates of monthly flow that extend back in time many centuries, water managers can challenge systems models with a larger range of natural variability in drought and pluvial events and better evaluate extreme events with recurrence intervals longer than the observed record.
"Curation is going to be a big part of Eco Market in the next few months, since now that we sell such a large range of items from a broad range of eco and natural sellers, our challenge is now being able to show the right kind of items to the right people based on their interests," Dainter notes.
The relevance of this model is not only based on the observation that many pathogens show a low species specificity but also on that a large range of hosts will encounter the same bacteria in their natural environment.
R. felis has been found extensively in commercial colonies and natural cat fleas, parasitizing a large range of mammalian hosts in several states of the United States (12, 13 ).
Such proteins act as energy-dependent efflux pumps capable of expelling a large range of xenobiotics, including doxorubicin and other cytotoxic drugs derived from natural products, out of the cell.
In grapevine, a ripening delay induced by the application of natural or synthetic auxins, including NAA, to berries before véraison was observed in a large range of cultivars [ 6, 11].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com