The first large randomized, controlled, prospective, evaluation of the PAC was published by Sandham and colleagues in 2003 [8].
However, robust evidence from large randomized, controlled trials is lacking.
He always preferred discerning studies in a small number of patients to large randomized, controlled trials of heterogeneous groups.
One large randomized controlled trial examining living conditions and obesity was the Move to Opportunity (MTO) study.
To date there have been no reports of large, randomized, controlled trials assessing the financial impact of GDFT.
The first large randomized, controlled, prospective, evaluation of the PAC was published by Sandham and colleagues in 2003 [ 8].
First, in large randomized controlled trials, the mortality in control groups has declined over time.
According to the Finnish Ministry of Education and Culture, "KiVa has been evaluated in a large randomized controlled trial including 117 intervention schools and 117 control schools.
Before tDCS can be approved by the F.D.A. and enter widespread use, there have to be large randomized controlled trials.
Lind and colleagues48 performed a large randomized controlled trial of on-demand therapy in 424 patients with nonerosive GERD.
Large randomized controlled trials with unselected patients, using morbidity and mortality as outcomes, are needed.
