Sentence examples for large proof of from inspiring English sources

Compared to many previous studies, including a relatively large proof of concept study of metyrapone augmentation of conventional antidepressants [ 33], the ADD study is recruiting from a broad population of patients including those from both primary and secondary care.

Furthermore, we showed, through a large proof-of-principle experiment, that weekly releases of OX3097D-Bol males into stable populations of caged wild-type olive fly could cause rapid population collapse and eventual eradication.

Thus, despite its limitations, this study provides supportive evidence to pursue additional studies of lebrikizumab as a potential novel therapeutic agent in asthma prior to embarking on large proof-of-concept studies.

We suggest new approaches to decrease risk of harm in pivotal Phase III RCTs in the critically ill including better surrogate endpoints in POP/Phase II RCTs to more accurately predict success in pivotal/Phase III RCTs, larger proof-of-principle/Phase II RCTs and use of response adaptive trial design in Phases II and III.

Previous clinical trials involving the treatment of patients with newly diagnosed T1D with potential immunotherapeutics have embarked on large clinical proof-of-concept trials without first establishing the correct dose of the experimental agent in order to achieve the desired immunological outcome.

Large-scale proof-of-concept prototypes were followed by micro-wire EDM fabrication of precipitation hardened stainless steel devices with flexible segment widths of 50 μm.

Additionally, a large-scale proof-of-capability calculation for 1 billion unknowns for the MHD Faraday pump problem on 24,000 cores is presented.

With 120,000 visitors in 2012, Jaipur's bookfest is among the world's largest, living proof of Indians' hunger for literary voices.

The block with the largest total proof of work embedded within it is chosen for the blockchain.

A large-scale proof of the enhancer activity of these sequences has recently been produced [ 9].

A large body of proof-of-principle experiments suggests that targeting MYC proteins may have considerable therapeutic benefit in human tumors (Felsher & Bishop, 1999; Soucek et al, 2008).