The phrase "large proliferation" is correct and can be used in written English.
It means a significant increase or growth in numbers or amount. You can use it when talking about a significant and noticeable growth or expansion of something. Example: The government's policies have led to a large proliferation of new businesses in the country.
Rat mammary glands contain a subpopulation of clonogenic epithelial cells with large proliferation and differentiation potentials.
"I think the blogosphere, the digital conversation," he said, "have not been a story about a large proliferation of substance and seriousness.
There is a large proliferation of clinical practice guidelines (CPG), there being doubts on inconsistencies between the recommendations made and internal incongruencies, that affect the role of the guidelines as instruments helping the clinicians.
Owing to the complex mechanisms of CHF there has been a large proliferation of the correlations, each having narrow range of validity, which shows that the empirical correlation is not an appropriate approach for the CHF prediction for a wide range of validity.
While Amazon has increasingly become a one-stop shop for some people, we're also seeing a large proliferation of online companies looking to connect with users wherever they happen to be spending the most time, whether that's on a social media platform, or on a site that caters to interests adjacent to the businesses's own — and most importantly not necessarily on the company's own web properties.
The large proliferation of maize crops across Earth has caused tiny, harmless fluctuations in the normal pattern of atmospheric carbon dioxide levels, since these crops photosynthesize large amounts of carbon dioxide during these times and this process sharply drops down during the late afternoon and evening.
Large proliferations of cytochrome P450 encoding genes resulting from gene duplications can be termed as 'blooms', providing genetic material for the genesis and evolution of biosynthetic pathways.
This suggests that the concerns about reduced selectivity among physiotherapy programs, specifically the types that are experiencing the largest proliferation, appear less warranted.
Italy has the largest proliferation of different kinds of sparkling wines of any country.
Compared to some other unicellular species, eg. Trichomonas vaginalis, Trypanosoma cruzi, and even the diplomonad Spironucleus vortens, the G. intestinalis genome has not undergone a massive repeat expansion, possibly due to evolutionary constraints that act upon the genome or because a large scale proliferation of mobile elements has not occurred.
Congestion and traffic-related pollution are typically the largest contributors to air pollution in cities. Rapid urbanization in developing countries has caused large-scale proliferation in motor vehicle use making cities increasingly congested and, subsequently, polluted.
